Lack of a hormone makes the overeat
London, Aug 10 of people: The scientists said that these people who miss leptin hormone eating with excess even when they are not scientists of hungry.
known as only the study of this hormone whichstops us eating too much could help them to develop a new class of drugs to treat obesity in a decade.
Leptin are produced by large cells and circulate in blood circulation to reach the brain where it acts to reduce the hunger and to increase the feeling of plenitude, according to the report/ratio in the question of Aug 9 of the team of Science journal.
A of researchers carried out by Paul C. Fletcher, a member of the university of the department of Cambridge of psychiatry, studied two people with a rare genetic disorder which stops the production of the leptin. The patients of
The ate excessive quantities of food, even things which they did not like, and were obese. However, when they were treated with the leptin, they ate less and lost the weight, brought back to health the researchers that gantries of Day.
The health showed to the two patients images of various foods while they recorded their activity of brain. The scientists noted that the activity stimulated by images in the sector of the brain called the areas striatal. These areas are associated the pleasant emotions and the area of desires.
One in particular, the accumbens of core, was strongly sensitive to the images of foods which the patients liked, the researchers found.
But when the patients were treated with the leptin, the images of foods produced an answer reduced in the brain and the researchers said that the answer was activated most of the time by foods the loved patients and only when they were arrangement of hungry.
” how the systems of brain act one on the other with the hormones that the stores of hunger and energy of signal will provide us a more complete image of the factors ordering of the spending patterns. They will take to us if all well beyond part of will reign and the simplistic claims about why some difficulties by ordering how much they have eat, “Fletcher said.
” such an arrangement will be a principal stage in the prevention and the treatment of obesity. In a paramount way, the observation that to like food is biologically conduit should encourage an attitude plus sympathetic nerve with people with problems of weight,” it was added.